abstract |
Provided are 2-aminopyridine compounds represented by the following formula and salts thereof, which have excellent adenosine receptor (A 1 , A 2a , A 2b receptor) antagonistic activity. [Wherein, R 1 represents a cyano group, a carboxyl group or a carbamoyl group which may have a substituent; R 2 represents a hydrogen atom, a hydroxyl group, or a C 1-6 alkoxy group which may have a substituent. Represents a C 6-14 aromatic hydrocarbon cyclic group which may have a substituent or a 5- to 14-membered aromatic heterocyclic group which may have a substituent; R 3 and R 4 represent A C 6-14 aromatic hydrocarbon cyclic group which may be the same or different and may have a substituent, a 5- to 14-membered non-aromatic heterocyclic group or a 5- to 14-membered aromatic heterocyclic group Group, etc. ] |