| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0ac9440355ad622000787e8d80a25147 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2603-74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C271-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-1024 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C239-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-117
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 |
| filingDate |
1987-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4eeb5355fd4fab210970203e431584d7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_afd4c516699f76c8bf9a8153844cb7ea
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b9a748d2f0dd109db92bdce4ae42f0c0 |
| publicationDate |
1989-03-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-S6483055-A |
| titleOfInvention |
Production of peptide and aspartic acid derivative |
| abstract |
PURPOSE:To produce a peptide in high yield and purity, by protecting a compound containing omega- and/or alpha-carboxyl group with 2-adamantyl, subjecting to peptide condensation reaction and deprotecting the product. CONSTITUTION:omega- and/or alpha-carboxyl group of an omega- and/or alpha-carboxyl- containing compound is protected with 2-adamantyl and the protected compound is subjected to peptide condensation. The reaction is carried out in a solvent (e.g. dichloromethane) in the presence of a condensation agent (e.g. dicyclohexylcarbodiimide) at -20-40 deg.C. The protecting group is eliminated with an acid (e.g. methanesulfonic acid) at -40-100 deg.C to obtain the objective peptide. A <=7C straight-chain amino acid having omega-and/or alpha-carboxyl group protected with 2-adamantyl and a peptide containing said amino acid are novel compounds. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0000470-A1 |
| priorityDate |
1987-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |