| abstract |
NEW MATERIAL:A compound of formula I [R<1>, R<2> are H, alkyl, alkoxy, alkoxycarbonyl, halogen; X is O, S, NR<3> (R<3> is H, alkyl, phenyl); Z is formula II-formula IV OR<9> (p, q are 1-3; R<4> is H, alkyl, aryl; R<5> is halogen, aryl; R<9> is H, alkyl, aryl); n is 0-2; m is 2-10; J, K are H, alkyl] and its salt. EXAMPLE:2-[{4-(2-Benzyloxyethoxy)-3-methylpyridin-2-yl}methylthio]benz imida zole. USE:A remedy for digestive ulceration with high safety. PREPARATION:For example, the reaction of a compound of formula V with a halide or sulfonate of formula VI (Y is halogen, sulfonyloxy) gives a com pound of formula I. |