http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6461467-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d93502a23a72b56472bc75854cfe7c60 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F20-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08F20-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-553 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 1987-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a7da0c3173a25d7792a0631b87b82502 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3ca6baef6da89fe0ae49ba0346f9ae77 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77ca8c3c38824e836c25df6abed76791 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f35381e97941b4158759d6a97e61f20d |
| publicationDate | 1989-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S6461467-A |
| titleOfInvention | 5-fluorouracil derivative |
| abstract | NEW MATERIAL:A compound expressed by formula I (R is H or methyl). EXAMPLE:1-Acryloyloxymethyl-5-fluorouracil. USE:An antiulcer agent having excellent polymerization activity as well as exhibiting excellent antiulcer activity in case of itself or polymerized product, or intermediate therefor. PREPARATION:A compound expressed by formula II obtained by reacting 5- fluorouracil with formalin according to ordinary method is reacted with (meth) acrylic acid and thiophenol in a proper solvent to afford a compound expressed by formula III, which is condensed in a proper solvent in the presence of a condensing agent and base to give a compound expressed by formula IV, which is then converted into sulfoxide in a proper solvent using an oxidant and heated to provide the compound expressed by formula I. The compound expressed by formula I is also obtained by reacting (meth)acrylic acid halide with 1,3- dihydroxymethyl-5-fluorouracil according to ordinary method. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10228365-B2 |
| priorityDate | 1987-08-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 34.