http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6460398-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_52a65b677bbedbe7bf090dd556a7cc43 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P41-004 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P17-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00 |
filingDate | 1987-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51e831f3661ff88cdf33b5ced99ac9cb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_39a32277d711f2cbcbcd8bbd289f2cd8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7523e37d16e59f9eaac9209d9b994299 |
publicationDate | 1989-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-S6460398-A |
titleOfInvention | Production of optically active compound having pyridine skeleton |
abstract | PURPOSE:To efficiently resolve the racemic mixture of a specific compound into an optically active ester and an enantiomer thereof, by biochemically subjecting the racemic mixture to an asymmetrical ester interchange reaction. CONSTITUTION:(R and S) compounds of formula I {X is a group of formula II-IV [Z<1>-Z<4> are hydrogen, halogen, cyano, amino, a group of formula V (W<1>-W<5> are hydrogen, halogen, cyano, etc.), 1-20C alkyl or alkoxy]; Y is halogen, hydrogen, cyano or trifluoromethyl; R and Q are 1-20C alkylene; m and n are 0 or 1} are subjected to an ester interchange reaction with an ester (e.g.: triglyceride) preferentially reacting with either of the (R and S) compounds of formula I in the presence of an enzyme (e.g.: lipase) having an ability of the asymmetrical ester interchange reaction substantially in the absence of water. Thereby, the compounds are resolved into the optically active compound rich in either of the R- and S-isomers and an ester thereof. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9405637-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5635395-A |
priorityDate | 1987-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 61.