http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6456618-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fd26d5987f45582fc8727d7e592a2ba3 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-02 |
| filingDate | 1987-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab9f13e639eaff24af890fea32b3cd03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0544bfe23c7449de4616d4bddd9c3e05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a2e7c35e9b638f94ee3f9c4014b5ac07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e215099e9d4a88cc81aaccce788b8305 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7086af9d7ef5e749f1fa33a152c1bbf7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8587397d1eeb7df0ac0b1b7a8e88b916 |
| publicationDate | 1989-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S6456618-A |
| titleOfInvention | Sustained release steroidal rectal administration pharmaceutical |
| abstract | PURPOSE:To obtain the titled readily producible pharmaceutical, having a delayed elution rate of an active ingredient and long duration of sustained blood level without any side effects, by blending a fatty and oily base with prednisolone acetate which is a synthetic adrenocortical hormone having anti- inflammatory action. CONSTITUTION:A sustained release steroidal rectal administration pharmaceutical obtained by blending a fatty and oily base selected from the group consisting of animal and vegetable fats and oils, mineral oils and glycerol esters of fatty acids with prednisolone acetate. The amount thereof blended is preferably within the range of 0.1-20wt.%, especially 0.2-10wt.% in the rectal administration pharmaceutical, which is prepared by blending and dispersing the prednisolone acetate with the fatty and oily base according to a conventional method and forming a solid suppository having 30-37 deg.C melting point or filling the blend or dispersion in an injection type rectal administration tube. Furthermore, the aforementioned fatty and oily base is preferably a solid at ordinary temperature and has 26-37 deg.C, especially 30-37 deg.C melting point. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-0511310-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H04346916-A |
| priorityDate | 1987-08-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.