abstract |
NEW MATERIAL:A compound expressed by formula I (R is OH or H) or ester thereof of salt thereof. Further more, formestin A has the following physicochemical properties: appearance: white powder; melting point: 142-144 deg.C (decomposed); mass analysis SIMS: 852 (M+1); molecular formula: C38H57O15; molecular weight: 851.91; specific rotation: [alpha]D<20>=-15.6 deg. (C=1, methanol); solubility: soluble in dimethylsulfoxide, methanol, ethyl acetate, acetic acid and aqueous alkali solution and insoluble in chloroform and hexane; weakly acidic substance: etc. EXAMPLE:A compound expressed by formula II. USE:An antiulcer immunoactivating agent and remedy for microbism. PREPARATION:Bacterium strain such as Actinomadura roseoviolacea MH511-O'-F1 (FERM P-8721) is cultivated. |