http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6438066-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5dd705d47c296b33f27d388714b2084d |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-38 |
| filingDate | 1987-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_14a9a579e46ee0da2407b88dfb6773a1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab753db8cb4c86781dc494efcc16db58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_623f2cd3178152a58ada0305be75876e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_137b9fd9a3b60030fb25a43bc1fca2aa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37a78e0e77b301c87d50558d264c68d5 |
| publicationDate | 1989-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S6438066-A |
| titleOfInvention | Production of beta-substituted enamines |
| abstract | PURPOSE:To selectively obtain the titled compound under mild condition in high yield, by reacting a compound such as N-ethoxycarbonyl-3-bromo-2-(2- oxypropyl)pyridine with a strong base and reacting the product in the presence of an acid catalyst. CONSTITUTION:The objective beta-substituted enamines of formula III [e.g. N- ethoxycarbonyl-5-(2-oxypropyl)-1,2,3,4-tetrahydropyridine] is produced by reacting a compound of formula I (R<1> and R<2> are H or 1-3C alkyl; R<3> is 1-10C alkyl or phenyl; X is halogen) with a strong base such as 1,8-diazabicyclo[5,4,0]-7- undecene to form a carbon-carbon bond at the beta-position of N of the compound of formula I and reacting the resultant compound of formula II in the presence of a catalytic amount of an acid (e.g. d,l-camphorsulfonic acid). The compound of formula III is a useful synthetic intermediate for various drugs, perfumes and natural alkaloid compounds. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S61136950-A |
| priorityDate | 1987-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.