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filingDate 1988-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87b9610e23a44e5cf3299f601a80dcb6
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publicationDate 1989-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-S6425720-A
titleOfInvention Percutaneous absorption pharmaceutical
abstract PURPOSE:To obtain a percutaneous absorption pharmaceutical, by using a specific absorbefacient consisting of combination of a fatty acid ester with a specific N-acylsarcosine, etc., and capable of improving percutaneous absorbability and stability of nicorandils useful as a remedy for angina pectoris. CONSTITUTION:A percutaneous absorption pharmaceutical, obtained by blending nicorandil useful as the above-mentioned medicine and/or salts thereof with an absorbefacient consisting of combination of (A) a fatty acid ester, preferably an ester synthesized from a 10-18C fatty acid and a 1-20C alcohol, especially isopropyl myristate, etc., with (B) an N-acylsarcosine, fatty acid mono- or diethanolamides or alkylene oxide adducts thereof, preferably N-lauroylsarcosine, lauroylmono- or diethanolamide, etc., in a base and having excellent absorbability and stability of the aforementioned medicine.
priorityDate 1987-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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