http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6425716-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5929f2d6f4dba84be8dd3a8ba633db12 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1271 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-24 |
| filingDate | 1988-04-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_242e04168bb4551baa483c21b1e9432d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_664dfe59aef54646fe1b8e686fec2389 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c989eaadc33a42856108c4a9f9dd372b |
| publicationDate | 1989-01-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S6425716-A |
| titleOfInvention | Liposome pharmaceutical and production thereof |
| abstract | PURPOSE:To obtain the titled pharmaceutical, containing a phospholipid having saturated acyl groups and glycolipid having sialic acid groups as membrane constituent components, capable of a stably circulating through the body together with blood for a long period after intravenous administration and capable of increasing target effects of a drug on specific lesions. CONSTITUTION:A liposome pharmaceutical obtained by dissolving (A) a phospholipid having saturated acyl groups and (B) a glycolipid having sialic acid groups in an organic solvent, such as diethyl ether, adding a solution containing a drug (e.g. anticancer agent, antibiotic substance, antiprotozoal agent, enzymic agent, anticoagulant or antiallergic agent), emulsifying the resultant blend to provide a W/O type emulsion, evaporating and removing the organic solvent at <=40 deg.C under reduced pressure. Glycerophospholipids having saturated acyl groups or sphingophospholipids (e.g. phosphatidyl choline) are cited as the ingredient (A) and gangliodsides, etc., are cited as the ingredient (B). Especially, the titled pharmaceutical containing the anticancer agent sealed therein is capable of improving remedial effects by administration thereof in thermotherapy. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H0616536-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2005221329-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010181258-A |
| priorityDate | 1987-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.