http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6413022-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3e42114d4d0f2966f76ba69072658e0f |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-335 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D317-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D317-24 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-357 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-335 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-20 |
| filingDate | 1988-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_720ef709542ad7fa6043a1aefa738d80 |
| publicationDate | 1989-01-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S6413022-A |
| titleOfInvention | Drug composition containing mucolytic thio-dioxolane derivative |
| abstract | PURPOSE: To obtain a medicine composition containing thiodioxolane derivative, having mucus-decomposing activities and suitable for treatment for excess secretion of bronchial mucus by including a specific thiodioxolane derivative. CONSTITUTION: This medicine composition containing thiodioxolarne derivative having mucus-decomposing activities includes a compound of the formula C* represents an asymmetric center of the molecule; X is OH or SR" (R" is H or an acyl); R is H, a lower alkyl, a lower hydroxyalkyl or phenyl; R' is a lower alkyl, a lower hydroxyl alkyl, phenyl or (CH2 )n SR"[(n) is 1-3]}, e.g. 2 (acetylthio)-ethyl-1,3-dioxolane-4-methanol with 21 pharmaceutically permissible carrier. The compound of the formula is obtained by treating the corresponding dioxolane derivative with a suitable alkali thioacylate in a polar solvent at 25-80 deg.C to provide a thioester and hydrating the obtained thioester with an alkali. |
| priorityDate | 1987-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.