| abstract |
NEW MATERIAL:A 5-oxo-2-tetrahydrofuranecarboxylic acid derivative expressed by formula I (R 1 represents amino group or organic residue bound through N atom; R 2 represents carboxyl or derivative group thereof; n is 1 or 2). n EXAMPLE: 4-Nitrobenzyl 2-[(3S)-3-benzyloxycarbonylamino-2-oxopyrrolidin-1-yl]-5- oxotetrahydrofuran-2-carboxylate. n USE: An antimicrobial agent. n PREPARATION: A compound expressed by formula II (R 1 ' represents organic residue bound through N atom; R 2 ' represents group convertible into carboxyl group; R 3 represents hydrocarbon residue) is subjected to cyclization reaction, and, if necessary, further subjected to conversion reaction of group R 1 ' and/or group R 2 '. n COPYRIGHT: (C)1988,JPO&Japio |