http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6379874-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dfd617dc43a4c986d2dd81e4cb39d9dd |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4035 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-403 |
| filingDate | 1986-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1603901062a05a6d5784d1c14a4bc35f |
| publicationDate | 1988-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S6379874-A |
| titleOfInvention | Isoindole derivative |
| abstract | NEW MATERIAL:The compound of formula I (R 1 is H,lower alkyl, aryl, aralkyl, etc.; X is H or halogen; Y is carboxyl, tetrazolyl, etc.; n is 1W6). n EXAMPLE: Ethyl [(7-chloro-2,3-dihydro-1-oxo-2-phenyl-1H-isoindol-5-yl)oxy]acetate. n USE: Remedy for hypertension, etc., having diuretic and hypotensive activities accompanying salt-excreting action. n PREPARATION: The compound of formula I can be produced by reacting the compound of formula II (R 2 and R 3 are lower alkyl) with a halogenation reagent such as N-bromosuccinimide in the presence of a radical generator such as perbenzoic acid, etc., and reacting the reaction product with a primary amine of formula R 1 NH 2 . The reaction is carried out in a nonpolar organic solvent such as carbon tetrachloride at room temperature W 120°C. n COPYRIGHT: (C)1988,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5350761-A |
| priorityDate | 1986-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 30.