Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bad11c717dfcc092b7665c1c32a2d691 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c999fee6428152a996011d506925c2d7 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D477-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C271-22 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D477-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D477-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C239-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 |
filingDate |
1986-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f610ee2a62660380f46b25f840e0618 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_371047f7aa1ebec21e86861fc4188954 |
publicationDate |
1988-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
JP-S6372667-A |
titleOfInvention |
Amino acid derivative, production and use thereof |
abstract |
NEW MATERIAL:A compound shown by formula I [R 1 is organic group reductively eliminable under acidic condition; R 2 and R 5 are H or carboxyl- protecting group; R 3 is alkyl, OH, methoxy or acetoxy; R 4 is ethyl, i-propyl or CH 3 CR 6 (OR 7 ) (R 6 is H or methyl; R 7 is OH-protecting group)]. n EXAMPLE: 2(S)-Benzyloxycarbonylamino-5-keto-6-t-butyloxycarbonyl-octanoic acid benzyl ester. n USE: An intermediate for producing carbapenam or carbapenem such as β-lactam antibiotics, etc., having excellent antibacterial action. n PREPARATION: A lithium enolate of a carboxylic acid ester shown by formula III is added to a pyrrolidonecarboxylic acid ester shown by formula II containing protected amino group and carboxyl group, which is subjected to ring formation to give a compound shown by formula I. n COPYRIGHT: (C)1988,JPO&Japio |
priorityDate |
1986-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |