http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6368096-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5e3324a35e1615e6eede6df1be26b7dd |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 |
filingDate | 1986-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eeb55b2a8c591dbad76553317511aaf1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f6b895cfe1e5a31b585694a009da318 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1dc525d7a96feec40a794ca2a9b808c |
publicationDate | 1988-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-S6368096-A |
titleOfInvention | Production of glutathione by bioreactor |
abstract | PURPOSE: To produce glutathione in high conversion, by passing a substrate through from a reactor having high reactivity to a reactor having low reactivity in plural column reactors packed with an immobilized microorganism capable of producing glutathione. n CONSTITUTION: A microbial cell prepared by introducing a plasmid obtained by integrating a gene of γ-glutamine-L-cysteine synthetase of Escherichia.coli variant and a gene of glutathione synthetase into a plasmid vector to strains such as Escherichia.coli, etc., and propagating and replicating the strains is immobilized on a carrier to provide an immobilized microorganism capable of producing glutathione. Then, plural column reactors packed with the immobilized microorganism one linked. A substrate solution is passed through the reactors to react the substrate with the microorganism and the immobilized microbial cell is renewed in turn from a reactor having reduced reactivity in glutathione production. Then, the substrate solution is passed through from a reactor having high reactivity to a reactor having low reactivity to react the substrate with the microorganism. n COPYRIGHT: (C)1988,JPO&Japio |
priorityDate | 1986-09-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 93.