http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6357574-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6cfc033f059d282fcd915bc8be2ae53f |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-58 |
| filingDate | 1986-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b6e0afeab3cabaccbffdf3c64fd16c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f84ec2cd306edf7bcd8abcd56b3c323 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e0549c31824ad6c720999c3d5532f7e |
| publicationDate | 1988-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S6357574-A |
| titleOfInvention | Production of imidazoles |
| abstract | PURPOSE: To produce the titled compound in high purity and yield even under a reaction condition of high concentration, by reacting a glyoxal compound with an aldehyde in the presence of a specific weakly acidic ammonium salt while controlling the pH of the reaction system within a specific narrow range. n CONSTITUTION: Ammonia is added to an aqueous solution or slurry of an aliphatic dibasic acid having a dissociation constant of ≤1/10 2 (especially preferably succinic acid, adipic acid or fumaric acid) to adjust the pH to 4W7. Glyoxals of formula I (R 1 and R 2 are H or methyl (e.g. methylglyoxal) is made to react with aldehydes of formula II (R 3 is alkyl, etc.) (e.g. formaldehyde) in the above solution or slurry. Ammonia is added to the system during the reaction to keep the pH of the reaction liquid constantly to 4W7, preferably 5W6. The produced aliphatic dibasic acid salt of imidazoles is separated from the system and an alkali is added to the salt to separate and remove the aliphatic dibasic acid and obtain the objective imidazoles of formula III (e.g. 4-methylimidazole). n COPYRIGHT: (C)1988,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-116396224-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-102199126-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100456092-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-0240454-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2004513941-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007095983-A |
| priorityDate | 1986-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 34.