http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6345299-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_39c3a06706e79b48ef4d7b444ec7faaf |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-37 |
| filingDate | 1986-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9488707e2babc5988303950bc9c2dbe1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6949c480b071fdd22fa111f160321a63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ef0480f7c1b1d89d4ded1f96bfd4cf8 |
| publicationDate | 1988-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S6345299-A |
| titleOfInvention | Peptide derivative |
| abstract | NEW MATERIAL:The compound of formula R1-Ile-Phe-Thr-Phe-Arg-R2 (R1 is H or amino-protecting group; R2 is group of formula I or II). EXAMPLE:The compound of formula H-D-Ile-Phe-Thr-Phe-Arg-pNA.HCl (pNA is p-nitroaniline). USE:A color-developing or fluorescent substrate for the determination of an active protein Ca of protein C which is a coagulation enzyme precursor. It enables accurate determination of the enzyme in short time. PREPARATION:The objective compound can be produced e.g. by reacting arginyl p-nitroanilide dihydrochloride with an amino-protected isoleucylphenylalanylthresonylphenylalanine in an inert solvent such as THF using diphenylphosphoric acid azide as a condensation agent at 0 deg.C- room temperature and, if necessary, the amino-protecting group is removed from the product. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2003014197-A |
| priorityDate | 1986-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.