http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6335580-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_620ecb9324409347c27e96b6071503ee |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D501-18 |
filingDate | 1986-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_840a432842f0c7a300b3949fec723a55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_88aa150d6373a87863d44f3df2e26a46 |
publicationDate | 1988-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-S6335580-A |
titleOfInvention | Production of novel 7-amino-3-heteroxyclic-thiomethyl-delta3-cephem-4-carboxylic acid |
abstract | NEW MATERIAL:The compound of formula I (R is lower alkyl) and its salt. n EXAMPLE: 7-Amino-3-(acetonyl-4-pyridiniothiomethyl)-3-cepham-4-carboxylate disulfate. n USE: A medicine. A production intermediate for a cephalosporin compound such as (Z)-7-[α-(2-amino-4-thiazolyl)-α-(methoxyimino)acetamido]-3-(1-acetonyl-4- carboxylate dinitrate) exhibiting excellent antibacterial activity against wide variety of bacterial strains belonging to Gram-positive bacteria and Gram-nega tive bacteria. n PREPARATION: The objective compound of formula I can be produced in high yield and purity on an industrial scale, by reacting 7-amino-cephalosporin compound of formula II or its salt with 2- or 4-thiopyridone or 1-substituted-3- mercatptopyridinium of formula III, formula IV or formula V in chlorosulfonic acid, fluorosulfonic acid or sulfuric acid under cooling or at room temperature. n COPYRIGHT: (C)1988,JPO&Japio |
priorityDate | 1986-07-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.