http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S63296-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c07d3133ffb87f20fc80c68aebd2a128 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a187da1bd4b3f5b8d74a8537cb6817a |
classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-465 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 |
filingDate | 1986-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f78f4456f51c9d712853a3e9520c12a2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_092e087e1b83d49d9c8ed2ec95e754a9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee910e4796d82d4614572e5a4306bc5a |
publicationDate | 1988-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-S63296-A |
titleOfInvention | Production of thiostrepton |
abstract | PURPOSE: To produce thiostrepton, by culturing a thiostrepton-producing microbial strain in a culture liquid preventing the deficiency of oxygen concentration by aeration and agitation and intermittently adding a nutrient source when the pH of culture liquid is increased. n CONSTITUTION: A microbial strain capable of producing thiostrepton, e.g. Streptomyces laurentii (ATCC 31255) or Streptomyces azureus (W.C. 3705) is cultured in a medium containing a carbon source, nitrogen source, inorganic substance, etc., under aerobic condition such as aeration and agitation, preferably at 5W9 pH and 22W32°C for 3W10 days. When the dissolved oxygen concentration is lowered to 1W6ppm after the start of culture, it is maintained preferably at 3W5ppm. When the pH is increased by the consumption of the carbon source in the culture liquid, a nutrient source is intermittently added to the medium at a rate of 0.3W1.0g/dl of carbon source and 0.1W0.5g/dl of nitrogen source at a time. n COPYRIGHT: (C)1988,JPO&Japio |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2010190842-A |
priorityDate | 1986-06-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.