http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S63284172-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69c0ba7037f9003fddd25919eee4a97a |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-04 |
| filingDate | 1987-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_476d4101ffb92d1ab2995186988ae731 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7cecb8691bc800d32de587e65faa44ca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_374edb7a1f1abfbb4593027668414f50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6e3369646f77b4763c375dddc174f731 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0e87559d3a0f94b9a1b4170dde048b1f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_492a6ee658bb4302f3348298392c9743 |
| publicationDate | 1988-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S63284172-A |
| titleOfInvention | Novel 4-aminoquinazoline derivative, production thereof and antiulcer agent containing said derivative |
| abstract | NEW MATERIAL:A compound expressed by formula I [R 1 is H, halogen or (F-substituted) lower alkyl; R 2 is H, lower alkyl, cycloalkyl, arylalkyl or (substituted) phenyl; R 3 is H, lower alkyl, (F-substituted) lower alkoxy, phenoxy, benzyloxy, etc.; X is S or S=O] and salt thereof. n EXAMPLE: 6-Chloro-4-phenylamino-2-(2-pyridylmethylsulfinyl)quinazoline. n USE: A stable medicine and antiulcer agent, having inhibitory action on gastric acid secretion, cytophylactic action and high safety and useful as a preventive and treating agent for gastric and duodenal ulcer, gastritis, etc. n PREPARATION: A 4-amino-2-mercaptoquinazoline derivative expressed by formula II is reacted with a pyridine derivative expressed by formula III (Y is halogen or acid residue of active ester) to provide the compound expressed by formula I (X is S), which is then treated with an oxidizing agent to afford the compound expressed by formula I (X is S=O). n COPYRIGHT: (C)1988,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-103709144-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106380465-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-106380465-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-100397792-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104119319-A |
| priorityDate | 1987-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.