http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S63284170-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a392a58e604548cc1ee8893b074a44d8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8ed387114397a9113dc31d35b11ee6b4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_eebd94dd108d74a49ab9415252e5e281 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-381 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-38 |
| filingDate | 1987-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f17dc6b6a81d9910ab74fdfa7c32015c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d103ec4ba0e9b9df6313954a9bce829a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_268a7f7216c71208362140ec34bbc322 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78b90f407e3cad4bdf56d5bafa994497 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba542f282ff73ebd1fc83a22198a2738 |
| publicationDate | 1988-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S63284170-A |
| titleOfInvention | Novel guanidinomethyl-thiophenecarboxylic acid derivative |
| abstract | NEW MATERIAL:A 5-guanidinomethyl-thiophene-2-carboxylic acid derivative expressed by formula I (R is H or lower alkyl) or salt thereof. n EXAMPLE: Ethyl 5-guanidinomethyl-thiophene-2-carbonylaminobenzoate. n USE: A medicine and active ingredient in antipeptic ulcer agents having low toxicity and inhibitory activity against 15-hydroxyprostaglandin dehydrogenase and considered as usable for curing and treating symptoms, such as gastric and duodenal ulcer gastritis, enteritis, etc. n PREPARATION: For example, 5-guanidinomethyl-thiophene-2-carboxylic acid expressed by formula II or a reactive derivative thereof is reacted with a 2- aminobenzoic acid derivative expressed by formula III (R 3 is lower alkyl) or reactive derivative at the amino group thereof to provide the compound expressed by formula I (R is H), which is hydrolyzed to afford the compound expressed by formula I (R is lower alkyl). n COPYRIGHT: (C)1988,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2006503810-A |
| priorityDate | 1987-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 38.