http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6327463-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5e3324a35e1615e6eede6df1be26b7dd |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C217-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-00 |
| filingDate | 1986-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d94b6a498efa071a47875992a762984f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b93615a4adb54482c1e3abcf0ce96025 |
| publicationDate | 1988-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S6327463-A |
| titleOfInvention | Production of deacetyl moxisylyte |
| abstract | PURPOSE: To obtain the titled compound having sympathetic nerve suppressing action and useful as a synthetic intermediate for cerebral circulation improver, with simple process, by oxidizing thymol with persulfuric acid, reacting with dimethylaminoethyl chloride and hydrolyzing the reaction product. n CONSTITUTION: Thymol of formula I is made to react with persulfuric acid at 0W40°C in a solvent such as water-acetone in the presence of an alkali to obtain a phenyl sulfite derivative, which is converted to an ether compound of formula II by reacting with dimethylaminoethyl chloride in a solvent such as dioxane in the presence of an alkali at a temperature between 50°C and the boiling point of the solvent. The ether is hydrolyzed e.g. with hydrochloric acid at 60W100°C to obtain the objective compound of formula III. The amount of persulfuric acid is 1W1.5mol per 1mol of thymol. n COPYRIGHT: (C)1988,JPO&Japio |
| priorityDate | 1986-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 39.