| abstract |
NEW MATERIAL:The compound of formula I [R 1 is H, halogen or lower alkyl; R 2 and R 3 are hydrocarbon group; R 4 and R 5 are H or lower alkyl; R 2 , R 3 , R 4 and R 5 may together with bonded carbon atom. form benzene ring; A is (lower alkyl-substituted) methylene, O or S; l and m are 0 or 1; n is 1W3; Het is group of formula IIWIV, etc. (R 6 is lower alkyl; R 7 is di(lower alkyl)- substituted carbamoyl); when A is O or S, Het is group of formula IV; when n≥2, Het is group of formula IV or V; when m is 1, R 2 , R 3 , R 4 and R 5 together with bonded C form benzene ring and Het is group of formula III, etc.]. n EXAMPLE: 2-{1-(1,2,3,4-Tetrahydroquinolyl)}methylpyridine. n USE: It exhibits antilipoperoxide action and is useful as a remedy and preventive for arteriosclerosis, etc. n PREPARATION: The compound of formula I can be produced e.g. according to the reaction formula. n COPYRIGHT: (C)1988,JPO&Japio |