http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S63270642-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_746d8243701ae4271b74368451625bee |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-343 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-94 |
| filingDate | 1986-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61b334c22cd7ebaa0ca505975117a349 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1fe29ec87f56a2c8ec1029e783d3587d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41cab7417a58249a458697407aaae2cd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d48d345ad6360bffd8724324d25da3a7 |
| publicationDate | 1988-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S63270642-A |
| titleOfInvention | Production of naphthalene derivative |
| abstract | PURPOSE: To obtain a 6-methoxy-5-trifluoromethyl-1-naphthalenecarboxylic acid industrially and advantageously, by reacting a 5-iodine compound corresponding to the aimed compound with a trifluoroacetate. n CONSTITUTION: A compound shown by formula I (R is lower alkyl) is reacted with a salt of trifluoroacetic acid such as an alkali metal or alkaline earth metal salt, especially sodium salt in the presence of a proper catalyst such as cuprous iodide or cuprous bromide, especially cuprous iodide and in a proper solvent preferably N-methylpyrrolidone or N,N-dimethylformamide at 150W200°C, preferably about 160°C to give the aimed compound shown by formula II useful as an intermediate for a compound shown by formula III (aldose reductase useful as a remedy for diabetic complication) from relatively inexpensive raw materials advantageously without requiring a specific equipment. n COPYRIGHT: (C)1988,JPO&Japio |
| priorityDate | 1986-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.