| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_24aca9ded2638ea793d05360dde7a4a0 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F7-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C49-707 |
| filingDate |
1987-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f257e63f6f2ea4841148a14cac14be01
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81c2601e3a078af862d482adb01fbd92
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cde3c96bc4b125f7a616143d428059f6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8619dddf9dff61302ad576a03cb75078
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf1279d98782c00b7ed8767a8017b2f8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6a48cb8be90afcd3b9f41ff9c47b2ea2 |
| publicationDate |
1988-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-S63254995-A |
| titleOfInvention |
Production of optically active hydroxycyclopentenones |
| abstract |
PURPOSE: To readily obtain the titled compound useful as an intermediate for prostaglandin derivatives which are medicines in good yield, by reacting dl- cyclopentenone esters having a specific structural formula with esterase and carrying out asymmetric hydrolysis. n CONSTITUTION: dl-Cyclopentenone esters expressed by formula I (R 1 is alkyl; R' is hydroxyl group-protecting group; n is 4W8) are reacted with esterase and asymmetrically hydrolyzed to afford the aimed optically active hydroxycyclopentenones expressed by formula II (R is H or hydroxyl group- protecting group; mark * indicates asymmetric carbon). Furthermore, the above- mentioned hydrolysis is normally carried out by vigorously stirring in a buffer solution at 10W60°C for 3W70hr. n COPYRIGHT: (C)1988,JPO&Japio |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-H02250847-A |
| priorityDate |
1986-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |