http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S63245695-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3f5ef33cec3537b306a172695f828500 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00 |
| filingDate | 1987-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ff4bc3fcf5dd5c3c161df5c5077a53a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_65b8aa0f3d02f5d0be8d8be9cbb01f55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b975adbaf5d450014f90098223a6a8de |
| publicationDate | 1988-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S63245695-A |
| titleOfInvention | Production of optically active sulfur-containing carboxylic acid ester and antipodal sulfur-containing carboxylic acid thereof |
| abstract | PURPOSE: To readily obtain the titled carboxylic acid useful for synthesizing various physiologically active substances, etc., in good yield, by reacting a specific carboxylic acid with a microorganism having the ability to asymmetrically esterify sulfur-containing carboxylic acids, etc., in an aerobic aqueous solvent. n CONSTITUTION: A strain, such as the genus Candida, capable of asymmetrically esterify sulfur-containing carboxylic acids is cultivated in a desired synthetic culture medium at pH3W11 and 20W50°C to provide microbial cells, which are then treated to afford a cell-free extract. The resultant extract is subsequently suspended in an aqueous solvent, such as phosphoric acid based buffer solution, or nonaqueous solvent, such as alcohol, and 0.01W50wt.% sulfur-containing carboxylic acid expressed by the formula [R 1 is H, (ar)alkyl or aryl; R 2 is alkyl; n is 1W20] to aerobically carry out asymmetric esterification reaction. The reaction is continued until the d-isomer of the carboxylic acid is completely esterified to afford a reaction solution, which is then extracted, separated and purified to recover the aimed optically active sulfur-containing carboxylic acid ester and antipodal carboxylic acid thereof. n COPYRIGHT: (C)1988,JPO&Japio |
| priorityDate | 1986-11-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 19.