http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S63238016-A

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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-455
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-48
filingDate 1987-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1004b7bf2599db852be2f7ee9c76750
publicationDate 1988-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-S63238016-A
titleOfInvention Soft capsule containing nicardipine hydrochloride
abstract PURPOSE: To provide a soft capsule composed of a content obtained by dissolving nicardipine hydrochloride in a specific mixed solvent and a capsule skin containing opacifying agent, etc., capable of stably keeping said drug over a long period and allowing the drug to be easily absorbed to develop sufficient effect when administered into a body. n CONSTITUTION: The objective soft capsule is composed of (A) a content produced by dissolving nicardipine hydrochloride in a mixed solvent consisting of a polyalkylene glycol having a molecular weight of 200W600 (preferably polyethylene glycol 400) and an alkylene glycol (preferably propylene glycol) at a weight ratio of 100:(10W25) and (B) a capsule skin containing an opacifying agent (e.g. titanium oxide or red iron oxide) and/or an ultraviolet absorber having absorption band in visible light range (e.g. Red No.2 or Yellow No.4). The concentration of nicardipine hydrochloride in the content (A) is preferably 2W10wt.%. The drug effect can be quickly exhibited by administering the soft capsule as a sublingual capsule and the capsule can be used as a remedy for stenocardia to which quick effect is required. n COPYRIGHT: (C)1988,JPO&Japio
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priorityDate 1987-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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