http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S63233948-A

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filingDate 1987-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_80cf44d03a3e55c9ceb800e4023451fc
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publicationDate 1988-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-S63233948-A
titleOfInvention Alpha-(3-(1-phenylethenyl)phenyl)propionic acid and alkyl ester thereof
abstract NEW MATERIAL:An α-[3-(1-phenylethenyl)phenyl]propionic acid shown by formula II (R is H or 1W4C alkyl) and an alkyl ester thereof. n USE: An intermediate for synthesizing α-[3-(1-phenylethenyl)phenyl]propionic acid (trade name ketoprofen) useful as a drug such as anti-inflammatory drug and analgesic inexpensively, in high yield and readily. n PREPARATION: A 1-(3-vinylphenyl)-1-phenylethylene shown by formula III is hydroesterified according to well-known method to give a compound shown by formula II. This compound is oxidized with an oxidizing agent or with molecular oxygen in the presence of an oxidation catalyst to give the above- mentioned drugs readily. n COPYRIGHT: (C)1988,JPO&Japio
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4999450-A
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type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 29.