http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S6322556-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9c635b4aaf4f814f6396c5d878d053ff http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_151f1bc34a6ad88c064ab834688e8f7f |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C313-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D281-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B57-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-26 |
| filingDate | 1986-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f746ae5f3314e49709ffa446e0eca774 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c3ebd4b2d31c705c3c451e25d9183da http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ca33f6a86127e4acc8c25c7eb3da5dc |
| publicationDate | 1988-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S6322556-A |
| titleOfInvention | Novel optically active carboxylic acid derivative l-lysine salt and its preparation |
| abstract | NEW MATERIAL:L-Lysine salt of d-threo-2-hydroxyl-3-(2-aminophenylthio)-3-(4- methoxyphenyl-)-propionic acid of formula I (*C means the carbon of the molecule which has been optically resolved). n USE: A synthetic intermediate of medicines. It is used as a synthetic intermediate of diltiazem hydrochloride, a remedy for angina pectoris and essential hypertension. n PREPARATION: dl-threo-2-Hydroxyl-3-(2-aminophenylthio )3-( 4-methoxyphenyl )-propionic acid of formula II and L-lysine or a salt of the propionic acid and L-lysine salt are allowed to react in a solvent such as methanol whereby the corresponding salt is obtained. Two kinds of the optically active diastereomers formed are separated by utilizing the difference in solubility between them and the compound of formula I is obtained as a hard soluble component. n COPYRIGHT: (C)1988,JPO&Japio |
| priorityDate | 1986-07-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.