http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S63225365-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bb4ee28d43b5e8d4a3c5141fa9bcfeb0 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-553 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 1987-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a0ed056872066151bb9590056738abe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6945bd4180c4db84fb99bac76de386b5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c7de7c44d7287f7aa6219fc9fa9437c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de7b45455fe163578ddf055f3c2619a8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5c19a87a5ce38d4ab985839d2a20cc3 |
| publicationDate | 1988-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S63225365-A |
| titleOfInvention | 5-fluorouracil derivative |
| abstract | NEW MATERIAL:The 5-fluorouracil derivative of formula I (R 1 is 1W10C fluorine-containing organic group which may contain S and/or O). n USE: A medicine. A carcinostatic agent, etc. It has excellent carcinostatic effect and low toxicity and is free from strong toxicity against digestive tract and dysautonomia in contrast with known 5-fluorouracil derivatives. n PREPARATION: The compound of formula I can be produced e.g. by reacting 5-fluorouracil of formula II with phosgene of formula COCl 2 in the presence of an organic base (e.g. pyridine) under cooling to -10W+10°C and reacting the resultant compound of formula III with a fluorine-containing amine of formula NH 2 R 1 at -10W+10°C. n COPYRIGHT: (C)1988,JPO&Japio |
| priorityDate | 1986-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 25.