http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S63216866-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0595453c678519c79a3ff454e21480a7 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-557 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-403 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-52 |
filingDate | 1987-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a67ba26b690ce5468a6282e009f830b |
publicationDate | 1988-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-S63216866-A |
titleOfInvention | 6-azaprostacyclin-analog compound |
abstract | NEW MATERIAL:The compound of formula I (R 1 is H, lower alkyl, alkali metal or polyhydroxylamine salt; R 2 is lower alkyl, aryl, cycloalkyl, etc.; R 3 is H or lower alkyl; R 4 is H or lower alkyl; X is >C=O, >SO 2 , -NH- or -CH 2 - or -CH 2 -; Y is trans- or cis-vinylene group; Z is 1W4C straight or branched chain or o-, m- p-substituted phenyl group). n EXAMPLE: N-(o, m or p)-carboxybenzoyl-6-aza-9-methano-protacyclin. n USE: A physiologically active agent having effect similar to prostaglandin. n PREPARATION: The objective compound can be produced by using the compound of formula II as a starting substance, converting the substance to the compound of formula III, reducing the produce, reacting with the compound of formula IV, converting CH 2 OAc group of the resultant compound of formula V into CHO group and reacting the product with dimethyl-2-oxoheptylphosphonate. n COPYRIGHT: (C)1988,JPO&Japio |
priorityDate | 1987-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 19.