http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S63216864-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b9822bceff022feda91b10019125e70f |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-052 |
| filingDate | 1987-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_202d48f90d70811a7f24b245aac00325 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1437f4405d66d7548bdb74495c5fd6a5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b466a633772259ebd6ee737b1d55300 |
| publicationDate | 1988-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S63216864-A |
| titleOfInvention | Indolyl ether derivative |
| abstract | NEW MATERIAL:The compound of formula I [X is H or arenesulfonyl; R is H, acyl or 2-(arenesulfonyl)-1,1-diazanediylalkyliden-1-yl]. n EXAMPLE: 4-Cyanomethyloxyindole. n USE: A synthetic raw material for 5-oxa-1,3,4,5-tetrahydrobenz-[cd]indole derivative of formula II (Y is H or lower alkyl) having antitumor activity. n PREPARATION: A compound of formula I wherein R and X are H can be produced by the thermal reaction of 4-hydroxyindole of formula III with a halogenonitrile in a solvent such as methyl ethyl ketone in the presence of a base such as K 2 CO 3 at 60W80°C. The produced compound can be converted to another compound of formula I wherein X is H and R is acyl by the Vilsmeier-Haack reaction or Friedel-Crafts reaction using an acid chloride as a reagent. n COPYRIGHT: (C)1988,JPO&Japio |
| priorityDate | 1987-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 23.