http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S63216851-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bc56cc6a1d317b2b28a2577329471b1b |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C215-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C67-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-00 |
filingDate | 1987-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d31fc6c01c436698e3867600f717b04 |
publicationDate | 1988-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-S63216851-A |
titleOfInvention | Production of 4-(4'-hydroxyphenyl)-2-aminobutane |
abstract | PURPOSE: To obtain a compound useful as a raw material for dobutamine hydrochloride which is a cardiotonicum in short process and high yield without discharging a substance which causes pollution, by hydrogenating 4-(4'- hydroxyphenyl)-3-butene-2-onoxime. n CONSTITUTION: 4-(4'-Hydroxyphenyl)-3-butene-2-onoxime is dissolved in an organic solvent such as methanol and reduced with hydrogen in the presence of a hydrogenation catalyst (e.g. Pd or Pt) to provide the aimed compound. The reaction is carried out in atmospheric pressure or higher, preferably in atmospheric pressure W 60atm. pressure. The catalyst is used in an amount of 0.5W30wt.%, preferably 1W10wt.% based on the oxime. The oxime which is a starting material is a precursor of 4-(4'-hydroxyphenyl)-2-butanone and synthesized from the reaction of 4-(4'-hydroxyphenyl)-2-butanone with hydroxylamine. n COPYRIGHT: (C)1988,JPO&Japio |
priorityDate | 1987-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 37.