http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S63215667-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_33dafb5bbc2ec47ebcb7becbbe60f704 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D227-087 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-445 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D223-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-22 |
filingDate | 1987-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc93d0a7eb2bdf021d634db3aa4533a9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a485e4c0b8fba745543afff70c6bcf35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06e02f052150a03d52346be3b2b10e6d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_718e1f63c4c6738184cb17afb74a780c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_92c3f6f9a2388f2b63a0cfe41686ba47 |
publicationDate | 1988-09-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-S63215667-A |
titleOfInvention | Drug for transcutaneous administration |
abstract | PURPOSE: To obtain the titled drug effective in promoting transcutaneous absorption of a medicine, having high safety and giving agreeable feeling to skin, by using an N-substituted lactam including novel compounds as an absorbefacient. n CONSTITUTION: An N-substituted lactam of formula I (m is 2W4; n is 3W5) such as an N-substituted lactam of formula II (p=m; q is 4 or 5) [e.g. 1-(3,7- dimethyloctyl)azacycloheptan-2-one which is a novel compound] is used as an absorbefacient. The objective drug can be prepared by compounding the compound of formula I with a medicine. The amount of the medicine is about 0.01W20wt.% based on the compound of formula I. The transcutaneous absorbefacient effect of the compound of formula I is remarkably developed especially for a medicine having moderate fat-solubility as well as water-solubility. The compound of formula I can be produced by reacting the corresponding lactam with a halide of formula III (X is halogen) in a hydrocarbon solvent in the presence of a base. n COPYRIGHT: (C)1988,JPO&Japio |
priorityDate | 1987-03-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.