http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S63203699-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cff62ee19588f053fe1f229df4e6c756 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-585 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-23 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-575 |
| filingDate | 1987-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cfe30541b329153cf02fa1a3c5bc50a6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e254595808f1a3f5f16fda0dce89b240 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_91b8882d4a94541cb5ae2f1c92a7b005 |
| publicationDate | 1988-08-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S63203699-A |
| titleOfInvention | Novel calcitonin derivative |
| abstract | NEW MATERIAL:A compound (salt) expressed by the formula [X is alanine or threonine; R is (substituted)benzyl]. n USE: A remedy for hypercalcemia, osteoporosis and bone Behcet's diseases. n PREPARATION: For example, BHA resin is placed in a reaction vessel for peptide solid-phase synthesis, reacted with a solution of an amino group-protected proline which is a C-terminal amino acid in dichloromethane in the presence of a condensing agent and linked to the resin. The amino-protecting group is then removed. Amino acids having protected amino groups are subsequently reacted according the amino acid sequence of the peptide and amino-protecting groups are removed. The above-mentioned operation is repeated to successively link the amino acids to afford a resin peptide, which is then treated with hydrogen fluoride to carry out elimination of the peptide from the resin and removal of all the protecting groups. Thereby the compound expressed by the formula is obtained. n COPYRIGHT: (C)1988,JPO&Japio |
| priorityDate | 1987-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.