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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-38
filingDate 1987-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26f5393ff772939a9813285ec00f34db
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publicationDate 1988-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-S63192396-A
titleOfInvention Production of l-isoleucine
abstract PURPOSE: To industrially and advantageously obtain the titled compound useful as a medicine, food, feed nutrient supplement, etc., by aerobically cultivating an ethanol-assimilating microorganism of the genus Brevibacterium while successively adding α-ketobutyric acid (salt) into a culture medium. n CONSTITUTION: An ethanol-assimilating microorganism, preferably Brevibacterium flavum MJ-233 (FERM-P No.3068), etc., belonging to the genus Brevibacterium is inoculated into a culture medium and ethanol is aseptically added. Cultivation is aerobically carried out while successively adding α- ketobutyric acid or a salt thereof, e.g. sodium α-ketobutyrate, etc., into a culture medium to afford the aimed compound. Furthermore, the α-ketobutyric acid or salt thereof is preferably successively added so that the concentration thereof in the culture medium may not exceed 30mM. n COPYRIGHT: (C)1988,JPO&Japio
priorityDate 1987-02-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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