http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S63179896-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_382ccfc2ebebcaee15aa7cda4cee86bc |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-91 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 1987-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_00f31b964d485d4de672ee22458c45ee http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e3d1cf7391d8bf3601810c0a383a3206 |
| publicationDate | 1988-07-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S63179896-A |
| titleOfInvention | Tumorous ergress factor and production thereof |
| abstract | NEW MATERIAL:Pure ergressin having the following properties. Apparent molecular weight measured by sodium dodecyl sulfate (SDS)-polyacrylamide gel electrophoresis (PAGE); 10,000 daltons. Basic protein. Stable even by heating at 56 deg.C for 30min. Stable within the pH range of 3.0-10.0. Having loose colony form inducing activity in renal fibroblastic cells of normal rats. Exhibiting imgrative activity from monolayer colonies of reanl epithelial cells fibroblastic cells. Indirect mitogen. USE:An immunological reagent for detecting and treating metastatic lesions. PREPARATION:For example, human metastatic melanoma M3827 clone 3 (ATCC No. CRL 9193) is cultivated in a serum0free culture medium and separation in carried out by molecular weight in the presence of 1.0M acetic acid to isolate a fraction having egressin activity and 25,000 molecular weight. Separation by cationic exchange, hydroxyapatite chromatography and hydrophobic separation, etc., are carried out to afford the aimed tumorous egress factor. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2007508816-A |
| priorityDate | 1986-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.