http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S63164895-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_be3928f66bb2545a8175c61c56146b9a |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43577 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-91 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-195 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435 |
| filingDate | 1986-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0cbf4deb1f4f3417ee22b84945902445 |
| publicationDate | 1988-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S63164895-A |
| titleOfInvention | Lectin-like protein originated from cultured cell, its production and antitumor agent composed mainly of said substance |
| abstract | PURPOSE:To obtain the titled antitumor agent useful as a clinical or diagnostic drug for man, stably on an industrial scale, by culturing a cell originated from embryo of Sarcophaga peregrina (a kind of flesh fly) and purifying supernatant of the medium e.g. by ion-exchange chromatography, etc. CONSTITUTION:Established cells (NIHSape-4) originated from embryo of Sarcophaga peregrina is cultured and the obtained supernatant of the medium is subjected to adsorption, separation and fractionation by ion-exchange chromatography and hydrophobic chromatography to eliminate existing inhibitor and then subjected to adsorption, separation and fractionation by affinity chromatography using galactose, etc., as a carrier. The fractionation product is purified to obtain the objective antitumor agent composed of a lectin-like protein having a molecular weight of about 185,000 (by gel filtration), exhibiting hemagglutination activity, etc., and dividable into 4 subunits having a molecular weight of about 32,000 (by SDS gel electrophoresis) and 2 subunits having a molecular weight of about 30,000. |
| priorityDate | 1986-09-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 35.