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filingDate 1986-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 1988-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-S63158000-A
titleOfInvention Integrated multi-layer analytic element for quantitative determination of total cholesterol
abstract PURPOSE: To suppress the inhibition to enzymatic activity and improve the storage stability of a reagent for the analysis of cholesterol, by adding a bile acid (derivative) or its salt and a specific alkylphenoxypolyethoxyethanol to the reagent. n CONSTITUTION: The objective integrated multi-layer analytic element for quantitative determination of total cholesterol is composed of a layer containing a hydrophilic polymer and a porous developing layer laminated to a light- transmitting water-impermeable substrate in the order and containing an enzyme having cholesterol esterase activity, a cholesterol oxidase, a peroxidase and a color-developing reagent composition. The above element further contains one or more compounds selected from bile acids, bile acid derivative and their salts and an alkylphenoxypolyethoxyethanol containing a polyoxyethylene chain having an oxyethylene unit number of ≥16. n COPYRIGHT: (C)1988,JPO&Japio
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