| abstract |
PURPOSE: To obtain the titled substance useful as a perfumery enhancer, etc., in high yield at high rate of reaction while suppressing side-reactions, by catalytically hydrogenating hydroxybenzoic acids in a secondary or tertiary alcohol solvent. n CONSTITUTION: The objective compound of formula II can be produced by hydrogenating a compound of formula I (R is H or 1W3C alkyl) in a secondary or tertiary alcohol solvent in the presence of a catalyst such as Pd-C under hydrogen pressure of 2W30kg/cm 2 at 80W200°C. Among the above alcohols, isopropyl alcohol is most preferable in view of suppressing effect of by-products, separation and recovery of the product after the reaction, etc. The amount of the solvent is preferably 1W3pts.wt. per 1pt.wt. of the compound of formula I. n COPYRIGHT: (C)1988,JPO&Japio |