| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1374dd16777534b65ad4422333245af8 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-525 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-525
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20 |
| filingDate |
1986-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50bf2573d87ec93fd2060f88ec3b2b30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f64e3fdfb5652ebcbb5329be5ed7ae9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad260c19afd2a4635c0ade016fa1281f |
| publicationDate |
1988-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
JP-S63148995-A |
| titleOfInvention |
Novel physiologically active polypeptide |
| abstract |
PURPOSE:To obtain an antitumorous active polypeptide having improved specific activity as well as stability, an extended range of reaction spectrum and reduced side effects, by modifying human tumor necrotic factor (TNF) protein. CONSTITUTION:A polypeptide having an amino acid sequence expressed by the formula or a polypeptide having Met (L-methionine) linked to the amino terminal thereof. A recombinant plasmid containing a DNA region is prepared to transform a microorganism therewith. Thereby the aimed polypeptide can be mass-produced. |
| priorityDate |
1986-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |