| abstract |
NEW MATERIAL:The compound of formula I [at least one of R 1 WR 4 is higher alkanoylamino, higher alkenylamino, higher alkoxycarbonylamino, higher alkylaminocarboxylamino, higher alkoxy(lower)alkanoylamino or higher alkylthiocarbonylamino which may have substituent group and the others are amino or acylamino; R a 5 WR a 9 are acyloxy; R 10 ' is OH, acyloxy, ar(lower)alkoxy or protected phosphonoxy]. n EXAMPLE: 1,3,6'-Tris-N-benzyloxycarbonyl-3"-N-trifluoroacetylkanamycin A. n USE: Antiviral agent, immunoactivation agent and their production raw material. n PREPARATION: The compound of formula III (R a 10 ' is acyloxy) can be produced e.g. by reacting a compound of formula II with a proper acylation agent in a solvent such as THF in the presence of a base such as triethylamine. n COPYRIGHT: (C)1988,JPO&Japio |