http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S63141963-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7ee684e0af67516b35b42adea885ac25 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-52 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J23-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-08 |
| filingDate | 1986-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a2ef68a4b65f06de211d1f6e4dad0f0 |
| publicationDate | 1988-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | JP-S63141963-A |
| titleOfInvention | Production of 1-benzyl-4-piperidinopiperidines |
| abstract | PURPOSE: To obtain the titled compound useful as an intermediate for synthesizing drugs inexpensively in high yield and in high quality, by reacting a readily obtainable 1-benzyl-4-piperidone with a piperidine and hydrogen in the presence of a compound catalyst. n CONSTITUTION: A piperidine shown by formula I (R 1 , R 2 and R 3 are H or lower alkyl) is reacted with 1-benzyl-4-piperidone and hydrogen by the use of a palladium catalyst as a catalyst preferably at 50W80°C under 10W70kg/cm 2 to give a compound shown by formula II. Piperidine, 2-methylpiperidine, etc., is used as the compound shown by formula I and the amount of the compound used is preferably 1W5mol based on 1mol 1-benzyl-4-piperidone as a raw material. A palladium catalyst supported on alumina, diatomaceous earth, etc., industrially sold on the market is used as the palladium catalyst and the amount of the catalyst used is preferably 0.1W20wt% based on the raw material. n COPYRIGHT: (C)1988,JPO&Japio |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10526288-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2008050307-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109311811-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109746004-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109746004-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017213245-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109311811-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-WO2017213245-A1 |
| priorityDate | 1986-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 39.