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filingDate 1986-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee86db766a97c6c0485f0a18408fa7ba
publicationDate 1988-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-S63137698-A
titleOfInvention Analytical element for measuring alkaline phosphatase
abstract PURPOSE: To obtain the titled analytical element, containing a substrate which is phosphoric acid esters of a self-nondeveloping compound capable of bimolecularly condensing in the presence of an oxidizing agent by action of an enzyme to form a coloring matter and a specific buffer agent in separate and different layers and having excellent sensitivity as well as preservation stability. n CONSTITUTION: A reagent layer containing a buffer agent having ≥8.0pKa value, e.g. 2-ethylaminoethanol, etc., is provided on a transparent support, e.g. polyethylene terephthalate, etc., and a porous developing layer containing a compound which is a phosphoric acid ester of a self-nondeveloping compound or a salt thereof, e.g. 5-bromo-4-chloro-3-indolyl phosphate toluidine salt, etc., and capable of bimolecularly condensing the nondeveloping compound formed in the presence of an oxidizing agent by action of the alkaline phosphatase in a liquid sample to form a coloring matter as a substrate for measuring alkaline phosphatase activity is provided thereon. Thereby the aimed analytical element having the substrate and buffer agent mutually present in the separate and different layers is obtained. n COPYRIGHT: (C)1988,JPO&Japio
priorityDate 1986-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 33.