http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-S63130585-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c4c14a3c2e541ec9969ff17176c1426d |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D455-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-435 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-18 |
filingDate | 1986-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7751cd46477ca924a2258166fd694b6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4fba820d1959c690d23a6350d025aa7a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9f464af6206692b8180313e26ddacb6 |
publicationDate | 1988-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | JP-S63130585-A |
titleOfInvention | 4-alkoxyquinoline compound and production thereof |
abstract | NEW MATERIAL:The compound of formula I (R is lower alkyl; X and Y are F or Cl). n EXAMPLE: 5-Chloro-4-ethoxy-6-fluoroquinoline. n USE: A production intermediate for novel 9-halogeno-5-alkyl-8-(substituted) piperazinyl-benzo[ij]quinolizine-2-carboxylic acid antibacterial agent. n PREPARATION: A 1,4-dihydro-4-oxoquinoline compound of formula II (e.g. 8- bromo-5-chloro-6-fluoro-4-oxo-1,4-dihydroquinoline) is alkylated with a lower alkyl halide of formula R-X 1 (X 1 is Br or I) (e.g. methyl iodide) in the presence of a base preferably at 20W80°C and the resultant compound of formula III is debrominated by the selective reduction with preferably a hydrogenation catalyst. n COPYRIGHT: (C)1988,JPO&Japio |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9221658-A1 |
priorityDate | 1986-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 26.