| abstract |
PURPOSE: To obtain the titled agent extremely lowering intraocular pressure, not showing reduction in intraocular pressure when intraocular pressure exhibits a normal value, free from side effects such as turbidity, hyperemia, etc., containing a substance acting on prostaglandin D 2 as an active ingredient. n CONSTITUTION: The titled agent containing a substance acting on prostaglandin D 2 as an active ingredient. A compound shown by the formula [X 1 -X 2 is -CH 2 -CH(OH)- or -NH-CO-; X is carboxy or derivative thereof; R 1 is bifunctional lower hydrocarbon residue; R 2 is saturated or monolefinic unsaturated lower hydrocarbon residue containing OH group at the third position counted from Y; R 3 is monofunctional saturated lower aliphatic hydrocarbon residue], salts thereof, etc., may be cited as the substance acting on prostaglandin D 2 . When the agent is used, the agent is blended with a drug carrier such as liquid excipient, etc., and administered in the form of drug preparation of ordinary use. n COPYRIGHT: (C)1988,JPO&Japio |