| abstract |
PURPOSE: To provide a carcinostatic agent containing a specific aromatic aldehyde derivative as an active component, active against a cell cancerized by SV 40 cancerizing virus and exhibiting high sensitivity. n CONSTITUTION: The objective agent contains, as an active component, a compound of formula (ϕ is benzene nucleus; R is alkyl, hydroxyalkyl, alkylaminoalkyl, pyridyl, piperidylmethyl, hydroxyphenyl or benzylideneaminoalkyl; R' is H, alkyliminoalkyl, alkylaminoalkyliminoalkyl or hydroxyalkyliminoalkyl; or ϕ is naphthalene nucleus, R is alkyl or hydroxyalkyl and R' is H) or its acid addition salt, e.g. N-benzylidene-t- butylamine. The ratio of the compound in the carcinostatic composition is preferably 0.3W15.0wt% for oral administration or transmucosal absorption and 0.01W10wt% for parenteral administration. n COPYRIGHT: (C)1988,JPO&Japio |