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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-32
filingDate 1986-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7bb0da73694cc1faef7a4d02e4afa2a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dec8268a51bebb1d9eb12d1097fb69cc
publicationDate 1988-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-S63105691-A
titleOfInvention Production of nicotinamide adenine dinucleotide
abstract PURPOSE:To efficiently produce the titled substance, by cultivating a variant strain of Candida boidinii in a culture medium containing methanol as a main carbon source. CONSTITUTION:A variant strain AP-15 or PC-31 strain obtained by varying Candica 25-A strain as a parent strain by an ultraviolet irradiation method as Candida boidinii Ad-15 (FERM P-8974) or Candida boidinii PC-31 (FERM P-8975) is cultivated in a culture medium containing methanol as a main carbon source. The culture medium of a normally used cultivation composition except about 0.5-3vol% methanol and about 0.1-0.5vol% quinolinic acid contained therein is used to aerobically cultivate the variant strain at about 25-33 deg.C. The obtained microbial cells are then collected and crushed to afford the aimed nicotinamide adenine dinucleotide from the resultant supernatant by a method using an organic solvent, adsorption, etc.
priorityDate 1986-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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