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filingDate 1985-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 1987-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber JP-S6284098-A
titleOfInvention Synthetic intermediate for echinocandin and production thereof
abstract NEW MATERIAL:A compound expressed by formula I [R 1 is H or tert- butylidemethyl; R 2 is H or tetrahydropyranyl; R 3 is H or tert-butyldimethylsilyl; A is hydroxyl group, pyridinethiol, etc.; B is H or formula II (D is H, benzyloxycarbonyl, etc.)] n EXAMPLE: ( 2S, 4R-N-Linoleyl-2-amino-4-O-Ct-butyldimethylsilyl )-5, 5-dimethoxy pentanolyl-O-tert-butyldimethylsilyl-threonyl-[( 4R )-4-hydroxy]prolyl-[( 3R )- hydroxy]homotyrosyl-threonly-[( 3S, 4S )-3-hydroxy-4-methyl]prolinamide. n USE: An antifungal and antiyeast agent. n PREPARATION: For example, a threonine derivative expressed by formula III is activated in an organic solvent and then reacted with a homotyrosine deriva tive expressed by formula IV and the protecting group is removed to afford the aimed compound expressed by formula I. n COPYRIGHT: (C)1987,JPO&Japio
priorityDate 1985-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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