| abstract |
PURPOSE: To obtain the titled compound useful as a raw material for producing tritoqualine, an antiallergic, by oxidizing the amino group of a tetrahydroisoquinoline compound to give a dihydroisoquinolinium salt and hydrolyzing it. n CONSTITUTION: The amino group of a tetraisoquinoline compound shown by the formula I is oxidized with an oxidizing agent such as a halogen, etc., to give a dihydroisoquinolinium salt shown by the formula II (A - is anion). Then, the compound is hydrolyzed preferably in the presence of a base at -20W100°C, to give the aimed compound. n COPYRIGHT: (C)1987,JPO&Japio |